yeast-based recombinant protein expression propietary technology

YEASTech® Platform

Yeast-based Recombinant Protein Expression
Propietary Technology

We develop what you need

YEASTprot

Recombinant proteins for nutraceutical, foodtech, and cell culture. Animal-free, stable, and highly functional.

YEASTzyme

Precision-fermented enzymes for diagnostics, industry, and research. Consistent, active, and scalable.

YEASTmAb

Yeast-derived monoclonal antibodies for IVD. Reproducible, ethical, and high-performance.

Gene to market: from genetic design to industrial-scale production

At Levprot Bioscience, our YEASTech® platform offers end-to-end development services for industrial-scale production of recombinant proteins in yeast.

From genetic design and strain engineering to bioprocess scale-up, protein characterization, and regulatory support, we provide a seamless workflow tailored to the needs of the life sciences, diagnostics, and next-gen food sectors. Our integrated expertise ensures high-yield, contaminant-free solutions with consistent quality and full compliance.

Through the YEASTech® Platform, we produce innovative proteins with functional benefits for health and nutrition. Our precision fermentation based approach ensures clean-label, high-digestibility, and bioactive stability—ideal for next-generation dietary supplements targeting sports nutrition, immune support, and healthy aging.

YEASTech® Platform Services

Genetic design

  • Gene design
  • Plasmid design
  • Codon optimization
  • Vector optimization

Strain engineering

  • Strain construction
  • Colony screening
  • Phenotypical characterization
  • Small-scale expression validation
  • Protein identity verification

Next-Generation Sequencing

  • Isolation of high-molecular-weight genomic DNA
  • Whole genome sequencing (WGS)
  • De novo genome assembly and annotation
  • Variant analysis (SNVs and InDels)
  • Genome comparison to reference strains
  • Taxonomic identity confirmation (ANI analysis)

Recombinant Proteins

YEASTech®
Platform

Regulatory service

  • Regulatory pathway guidance for
    Compliance support with audits
    and documentation traceability
  • Scientific advice for claims and
    labelling

Industrial-scale production

  • Expression media optimization
  • Industrial-scale fermentation process
  • Industrial-scale downstream processing

Pilot-scale process development

  • Expression media optimization
  • Pilot-scale fermentation process
  • Pilot-scale downstream processing

Lab-scale process optimization

  • Shake flask expression process
  • Small-scale downstream processing
  • Expression media optimization
  • Lab-scale fermentation process
  • Lab-scale downstream processing

Protein characterization

  • Functionality assay
  • Stability analysis
  • Physicochemical analysis
  • Protein identity verification

Quality control

  • Protein identity verification
  • Protein purity analysis
  • DNA contamination analysis
  • Stability analysis
  • Microbial analysis
  • Molecular biology grade analysis
  • Custom analysis

Preservation

  • Lyophilization
  • Spray-drying
  • Liquid stabilization
  • Long-term stability analysis

Genetic design

  • Gene design
  • Plasmid design
  • Codon optimization
  • Vector optimization

Strain engineering

  • Strain construction
  • Colony screening
  • Phenotypical characterization
  • Small-scale expression validation
  • Protein identity verification

Next-Generation Sequencing

  • Isolation of high-molecular-weight genomic DNA
  • Whole genome sequencing (WGS)
  • De novo genome assembly and annotation
  • Variant analysis (SNVs and InDels)
  • Genome comparison to reference strains
  • Taxonomic identity confirmation (ANI analysis)

Enzymes

YEASTech®
Platform

Regulatory service

  • Regulatory pathway guidance for
    Compliance support with audits
    and documentation traceability
  • Scientific advice for claims and
    labelling

Industrial-scale production

  • Expression media optimization
  • Industrial-scale fermentation process
  • Industrial-scale downstream processing

Pilot-scale process development

  • Expression media optimization
  • Pilot-scale fermentation process
  • Pilot-scale downstream processing

Lab-scale process optimization

  • Shake flask expression process
  • Small-scale downstream processing
  • Expression media optimization
  • Lab-scale fermentation process
  • Lab-scale downstream processing

Protein characterization

  • Functionality assay
  • Activity assay
  • Stability analysis
  • Physicochemical analysis
  • Protein identity verification

Quality control

  • Protein identity verification
  • Protein purity analysis
  • DNA contamination analysis
  • Activity assay
  • Stability analysis
  • Microbial analysis
  • Molecular biology grade analysis
  • Custom analysis

Preservation

  • Lyophilization
  • Spray-drying
  • Liquid stabilization
  • Long-term stability analysis

Antibody generation

  • Animal immunization
  • B-cell or hybridoma isolation
  • Antibody screening (ELISA, FACS)
  • Antibody sequencing
  • Humanization

Genetic design

  • Gene design
  • Plasmid design
  • Codon optimization
  • Vector optimization

Strain engineering

  • Strain construction
  • Colony screening
  • Phenotypical characterization
  • Small-scale expression validation
  • Protein identity verification

Monoclonal Antibodies

YEASTech®
Platform

Regulatory service

  • Regulatory pathway guidance for
    Compliance support with audits
    and documentation traceability
  • Scientific advice for claims and
    labelling

Industrial-scale production

  • Expression media optimization
  • Industrial-scale fermentation process
  • Industrial-scale downstream processing

Pilot-scale process development

  • Expression media optimization
  • Pilot-scale fermentation process
  • Pilot-scale downstream processing

Lab-scale process optimization

  • Shake flask expression process
  • Small-scale downstream processing
  • Expression media optimization
  • Lab-scale fermentation process
  • Lab-scale downstream processing

Protein characterization

  • Functionality assay
  • Stability analysis
  • Physicochemical analysis
  • Protein identity verification

Quality control

  • Protein identity verification
  • Protein purity analysis
  • DNA contamination analysis
  • Stability analysis
  • Microbial analysis
  • Molecular biology grade analysis
  • Custom analysis

Preservation

  • Lyophilization
  • Spray-drying
  • Liquid stabilization
  • Long-term stability analysis

Strain & Upstream Development

This initial stage lays the foundation for successful recombinant protein production. Levprot designs and engineers microbial strains tailored to each protein, selecting and optimizing genetic constructs for maximum yield and functionality. Through cutting-edge Next-Generation Sequencing (NGS) and iterative lab-scale optimization, we ensure that each strain delivers high performance in fermentation and downstream steps.
We offer a complete antibody development workflow, from animal immunization and B-cell or hybridoma isolation to antibody screening (ELISA, FACS), sequencing, and humanization.
We help design the ideal genetic sequence for the protein of interest, optimizing expression and functionality.
Levprot applies precision engineering techniques to generate robust yeast strains tailored to industrial protein production.
We use NGS tools to verify construct integrity and improve genetic stability of expression hosts.
We use NGS tools to verify construct integrity and improve genetic stability of expression hosts.

Process Scale-Up & Manufacturing

Once the strain and upstream conditions are optimized, we transfer processes to larger volumes. This stage includes pilot-scale trials to replicate lab results under realistic fermentation conditions, followed by full industrial-scale production that meets quality and regulatory standards. Preservation steps ensure long-term usability of the strain or product.
We bridge the gap between lab results and industrial production with scalable, reproducible pilot runs.
Our certified facilities are equipped to deliver full-scale protein manufacturing under high-yield conditions.
Customized storage and stabilization protocols ensure protein quality throughout shelf life and distribution.

Protein Analytics & Validation

Our analytical capabilities ensure each protein is correctly folded, functional, and compliant with quality standards. We perform in-depth protein characterization and systematic quality control to guarantee reproducibility, safety, and performance in the final applications.
We perform detailed biochemical and biophysical assessments to confirm the identity and functionality of each protein.
Our QC ensures compliance with batch specifications and regulatory standards, providing full documentation.

Compliance Support

Navigating the regulatory environment can be complex. Levprot offers guidance and documentation to support our clients in their applications, certifications, or regulatory submissions across diverse industries such as diagnostics, foodtech, or cosmetics.

From documentation to guidance, we help ensure your product meets the standards of pharma, food, and biotech industries.

Why Choose Levprot as Your Partner?

CMO

Contract Manufacturing Organization

We provide certified, scalable production of recombinant biomolecules tailored to your industrial needs from pilot batches to full-scale manufacturing.

CDO

Contract Development Organization

Our expert team supports your innovation pipeline with end-to-end development services, from genetic design to process optimization and scale-up.

CPO

Cooperative Project Organization

We partner closely with biotech teams to co-develop
strategic, high-impact solutions in Life Sciences, Cell Culture, and Nutraceuticals.

CRS

Core Reagent Solutions

Levprot supplies selected high-purity enzymes and recombinant proteins as essential raw materials for advanced research and diagnostics.

Yeast-based expression

Expertise in Yeast-Based Expression – High-yield, scalable, and industry-proven.

Regulatory compliance

Meeting the highest quality standards for biopharma and foodtech.

End-to-end process

Process Development from strain engineering to final product manufacturing.

Cost effective

Sustainable & Cost-Effective optimized processes for low environmental impact and cost efficiency.

Your Partner in Scalable Bioprocessing

Our state-of-the-art facilities and customizable services allow us to seamlessly transition from lab-scale to industrial-scale production, minimizing risks and optimizing time-to-market your needs.